4-cyano-1H-pyrrole-2-carboxylic acid → 4-[4-[(4-Cyano-1H-pyrrole-2-carbonyl)-amino]-3-(4-methyl-piperidin-1-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][N:21]([c:24]2[cH:25][c:26]([N:31]3[CH2:32][CH2:33][CH:34]([CH3:37])[CH2:35][CH2:36]3)[c:27]([NH2:30])[cH:28][cH:29]2)[CH2:22][CH2:23]1.[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:8](=[O:9])[OH:10])[nH:6][cH:7]1>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:8](=[O:10])[NH:30][c:27]2[c:26]([N:31]3[CH2:32][CH2:33][CH:34]([CH3:37])[CH2:35][CH2:36]3)[cH:25][c:24]([N:21]3[CH2:20][CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:23][CH2:22]3)[cH:29][cH:28]2)[nH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-daec0a43e2814a408265cb93509ae7c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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