6-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acid → Tert-butyl 3-[[(6-methylimidazo[2,1-b][1,3]thiazole-5-carbonyl)amino]methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate

HRID 313962Notes

Reaction equation

HRID 313962 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH2:15].[CH3:16][c:17]1[n:18][c:19]2[s:20][cH:21][cH:22][n:23]2[c:24]1[C:25](=[O:26])[OH:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH:15][C:25]([c:24]1[c:17]([CH3:16])[n:18][c:19]2[s:20][cH:21][cH:22][n:23]21)=[O:26]

Participants

3

Reactant 2

HCID 3299796-Methylimidazo[2,1-B][1,3]thiazole-5-carboxylic acidHCID 76739429Tert-butyl 3-(aminomethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate

Product 1

HCID 77222810Tert-butyl 3-[[(6-methylimidazo[2,1-b][1,3]thiazole-5-carbonyl)amino]methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate

Sources & evidence

ORD record
ord-719d5af398224a9ea425dfad033c1933
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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