4-Methyl-1,3-oxazolidin-2-one → N-[2-[4-(5-cyclopropyl-3-methyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)phenyl]methanesulfonamide

HRID 313974Notes

Reaction equation

HRID 313974 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([CH:28]4[CH2:29][CH2:30]4)[cH:25][c:26]3[CH3:27])[CH2:19][CH2:20]2)[c:6]([NH:8][S:9](=[O:10])(=[O:11])[CH3:12])[cH:7]1.[CH3:31][CH:32]1[NH:33][C:34](=[O:37])[O:35][CH2:36]1>>[c:2]1([N:33]2[CH:32]([CH3:31])[CH2:36][O:35][C:34]2=[O:37])[cH:3][cH:4][c:5]([C:13](=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([CH:28]4[CH2:29][CH2:30]4)[cH:25][c:26]3[CH3:27])[CH2:19][CH2:20]2)[c:6]([NH:8][S:9](=[O:10])(=[O:11])[CH3:12])[cH:7]1

Participants

3

Reactant 2

HCID 98554554-Methyl-1,3-oxazolidin-2-oneHCID 58484826N-{5-bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}methanesulfonamide

Product 1

HCID 76800492N-[2-[4-(5-cyclopropyl-3-methyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)phenyl]methanesulfonamide

Sources & evidence

ORD record
ord-47c53c3742a046309eb75de1e6a7f676
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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