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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31432Generated: October 25, 2026

2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole → 2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide

https://huagongshe.com/reaction/31432

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 11436693—
Reactant4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamideHCID 59791521—
Product2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamideHCID 44580420—

Reaction Steps

Example 2 was prepared using 2-(4-bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole and 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)benzamide (Intermediate 5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-17cbd27e0d9643aa95a8dc342e433e0a
Source noteuspto-grants-2008_09