Benzene → 1-Diphenylmethyl-4-chloromethylpiperidine

HRID 314340Notes

Reaction equation

HRID 314340 reaction equation
[S:1]([Cl:2])([Cl:3])=[O:4].[c:5]1([CH:11]([N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][OH:19])[CH2:16][CH2:17]2)[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:6][cH:7][cH:8][cH:9][cH:10]1.[cH:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[Cl:3][CH2:18][CH:15]1[CH2:14][CH2:13][N:12]([CH:11]([c:5]2[cH:6][cH:7][cH:8][cH:9][cH:10]2)[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:17][CH2:16]1

Participants

4

Reactant 3

HCID 241BenzeneHCID 24386Thionyl ChlorideHCID 21993744(1-Benzhydrylpiperidin-4-yl)methanol

Product 1

HCID 538573511-Diphenylmethyl-4-chloromethylpiperidine

Sources & evidence

ORD record
ord-3f024c2340194d4b8fd4abddc9bf5e48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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