Diethyl Ether → 1-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl-amino)-ethanone

HRID 314343Notes

Reaction equation

HRID 314343 reaction equation
[CH2:31]([O:32][CH2:33][CH3:34])[CH3:35].[Cl:13][CH2:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][CH:20]([CH2:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[CH2:21][CH2:22]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[NH:7][C:8](=[O:11])[CH2:9][O:10]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:12]1)[NH:7][C:8](=[O:11])[CH2:9][O:10]2)[CH2:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][CH:20]([CH2:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[CH2:21][CH2:22]1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 27636816-amino-3,4-dihydro-2H-1,4-benzoxazin-3-oneHCID 691000562-Chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone

Product 1

HCID 691004861-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl-amino)-ethanone

Sources & evidence

ORD record
ord-c33104cd48ae49d694c08e1ca4368b1c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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