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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 31439생성일: 2026년 10월 25일

N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]-2-pyrrolidin-1-yl-isonicotinamide → N-[2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamide

https://huagongshe.com/reaction/31439

반응식

참여 물질

역할이름HCID투입량
반응물N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]-2-pyrrolidin-1-yl-isonicotinamideHCID 11258289—
반응물2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 11436693—
생성물N-[2',6-Dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamideHCID 10479082—

반응 단계

Example 10 was prepared using 2-(4-bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole and N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)phenyl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamide (Intermediate 20).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07425555B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-f65794d9725d4afbaa1113cac5bdf9f9
출처 메모uspto-grants-2008_09