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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 314461Generated: October 29, 2026

Dichloromethane → trans-N-{4-[3-(4-hydroxy-piperidin-1-yl)-3-oxo-propoxy]-cyclohexyl}-N-methyl-4-trifluoromethyl-benzenesulfonamide

https://huagongshe.com/reaction/314461

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantPiperidin-4-olHCID 79341—
Reactanttrans-3-{4-[Methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-cyclohexyloxy}-propionic acidHCID 11538772—
Producttrans-N-{4-[3-(4-hydroxy-piperidin-1-yl)-3-oxo-propoxy]-cyclohexyl}-N-methyl-4-trifluoromethyl-benzenesulfonamideHCID 11294814—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-2968534c629241ad91ec3d74f3cb4654
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)