Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31448Generated: October 25, 2026

2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole → 6,2'-Dimethyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid thiazol-2-ylamide

https://huagongshe.com/reaction/31448

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 11436693—
Reactant4-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(thiazol-2-yl)-benzamideHCID 21914517—
Reactant4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamideHCID 86604696—
Product6,2'-Dimethyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid thiazol-2-ylamideHCID 10249810—

Reaction Steps

Example 19 was prepared using 2-(4-bromo-3-methylphenyl)-5-methyl-[1,3,4]oxadiazole and 4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamide (Intermediate 22).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-5d4f27f013974c239b0c96184fbc9768
Source noteuspto-grants-2008_09