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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 314486Generated: October 25, 2026

Hydrochloric Acid → 6-[2-[2-(cyclobutylmethoxy)-3-(difluoromethoxy)phenyl]ethenyl]-N-[4-(trifluoromethyl)-1,3-thiazol-2-yl]imidazo[2,1-b][1,3]thiazole-5-carboxamide

https://huagongshe.com/reaction/314486

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant2-Thiazolamine, 4-(trifluoromethyl)-HCID 1201417—
Reactant6-[2-[2-(Cyclobutylmethoxy)-3-(difluoromethoxy)phenyl]ethenyl]imidazo[2,1-b][1,3]thiazole-5-carboxylic acidHCID 67549460—
Product6-[2-[2-(cyclobutylmethoxy)-3-(difluoromethoxy)phenyl]ethenyl]-N-[4-(trifluoromethyl)-1,3-thiazol-2-yl]imidazo[2,1-b][1,3]thiazole-5-carboxamideHCID 75215945—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-1286eaed286c4bb487b81880e1c3e1a4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)