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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31451Generated: October 26, 2026

2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole → Thiophene-3-carboxylic acid[6,2'-dimethyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-yl]-amide

https://huagongshe.com/reaction/31451

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 11436693—
ReactantN-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamideHCID 21914662—
ProductThiophene-3-carboxylic acid[6,2'-dimethyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-yl]-amideHCID 58629795—

Reaction Steps

Example 23 was prepared using 2-(4-bromo-3-methylphenyl)-5-methyl-[1,3,4]oxadiazole and N-[4-methyl-3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]thiophene-3-amide (Intermediate 27).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-e9ac209cefc74836a49c6cf6132f5672
Source noteuspto-grants-2008_09