HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazole → 6-Methyl-4'(3-methyl-[1,2,4]oxadiazol-5-yl)-biphenyl-3-carboxylic acid cyclopropylamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazole | HCID 19703116 | — |
| Edukt | N-cyclopropylmethyl-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide | HCID 21914588 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 6-Methyl-4'(3-methyl-[1,2,4]oxadiazol-5-yl)-biphenyl-3-carboxylic acid cyclopropylamide | HCID 58629789 | — |
Reaktionsschritte
Example 24 was prepared using 5-(4-iodophenyl)-3-methyl-[1,2,4]oxadiazole (Intermediate 12) and N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (Intermediate 17) using DMF as the solvent.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425555B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-064939e146b0408faebd7cb67e48d9ae |
| Quellennotiz | uspto-grants-2008_09 |