HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 314526Generated: October 30, 2026
Chlorotrimethylsilane → 3-[1-(4-difluoromethoxy-benzenesulfonyl)-1H-indol-5-yl]azetidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/314526
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | 1,1-Dibromoethane | HCID 11201 | — |
| Reactant | Zinc | HCID 23994 | — |
| Reactant | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | Tert-butyl 3-iodoazetidine-1-carboxylate | HCID 11000522 | — |
| Reactant | 1-(4-difluoromethoxybenzenesulfonyl)-5-iodo-1H-indole | HCID 68596937 | — |
| Product | 3-[1-(4-difluoromethoxy-benzenesulfonyl)-1H-indol-5-yl]azetidine-1-carboxylic acid tert-butyl ester | HCID 68598167 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
| ORD ID | ord-9c2c686fea194b528d40443bf08007a7 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
|---|
