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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31453Generated: October 26, 2026

5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazole → Furan-3-carboxylic acid[6-methyl-4'-(3-methyl-[1,2,4]oxadiazol-5-yl)-biphenyl-3-yl]-amide

https://huagongshe.com/reaction/31453

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazoleHCID 19703116—
ReactantN-[4-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-furamideHCID 21914573—
SolventDimethylformamideHCID 6228—
ProductFuran-3-carboxylic acid[6-methyl-4'-(3-methyl-[1,2,4]oxadiazol-5-yl)-biphenyl-3-yl]-amideHCID 58629792—

Reaction Steps

Example 25 was prepared using 5-(4-iodophenyl)-3-methyl-[1,2,4]oxadiazole (Intermediate 12) and N-[4-methyl-3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-furamide (Intermediate 25) using DMF as the solvent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-8086e5d89385496481d1c37c2aabcef4
Source noteuspto-grants-2008_09