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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31462Generated: October 25, 2026

2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole → Furan-3-carboxylic acid[6-methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-yl]-amide

https://huagongshe.com/reaction/31462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazoleHCID 676569—
ReactantN-[4-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-furamideHCID 21914573—
SolventIsopropanolHCID 3776—
ProductFuran-3-carboxylic acid[6-methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-yl]-amideHCID 58629790—

Reaction Steps

Example 35 was prepared using 2-(4iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and N-[4-methyl-3-(4,4,5,5, -tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-furamide (Intermediate 25) with propan-2-ol as the solvent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-aff887a711d2461d9a906e471fe7312c
Source noteuspto-grants-2008_09