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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31465Generated: October 25, 2026

2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole → 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid thiazol-2-ylamide

https://huagongshe.com/reaction/31465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazoleHCID 676569—
Reactant4-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(thiazol-2-yl)-benzamideHCID 21914517—
Reactant4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamideHCID 86604696—
SolventIsopropanolHCID 3776—
Product6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid thiazol-2-ylamideHCID 10090936—

Reaction Steps

Example 38 was prepared using 2-(4-iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and 4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamide (Intermediate 22) with propan-2-ol as the solvent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-2694e2157cdf459d9a5f59f9b3c32dea
Source noteuspto-grants-2008_09