Acetonitrile → Ethyl 2-(isopropylamino)-4-(trifluoromethyl)thiazole-5-carboxylate

HRID 314757Notes

Reaction equation

HRID 314757 reaction equation
[CH3:20][C:21]#[N:22].[CH:1]([CH3:2])([CH3:3])[NH2:4].[Cl:5][c:6]1[s:7][c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[c:9]([C:11]([F:12])([F:13])[F:14])[n:10]1>>[CH:1]([CH3:2])([CH3:3])[NH:4][c:6]1[s:7][c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[c:9]([C:11]([F:12])([F:13])[F:14])[n:10]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 6363IsopropylamineHCID 1235240Ethyl 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate

Product 1

HCID 7174201Ethyl 2-(isopropylamino)-4-(trifluoromethyl)thiazole-5-carboxylate

Sources & evidence

ORD record
ord-25bde8cf7eb44191ade1255f4c015d38
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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