alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride → (1,4-Dibenzylpiperidin-3-yl) 3,3,3-trifluoro-2-methoxy-2-phenylpropanoate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([OH:21])[CH:11]([CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:22][O:23][C:24]([C:25](=[O:26])[Cl:27])([C:28]([F:29])([F:30])[F:31])[c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([O:21][C:25]([C:24]([O:23][CH3:22])([C:28]([F:29])([F:30])[F:31])[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)=[O:26])[CH:11]([CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-d3a38b540fec41daa9639ef447e6cd0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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