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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 314883Generated: October 26, 2026

Tetrahydrofuran → 4-Chloro-3-cyanomethyl-indole-1-carboxylic acid methylamide

https://huagongshe.com/reaction/314883

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantMethyl IsocyanateHCID 12228—
Reactant2,2,6,6-TetramethylpiperidineHCID 13035—
Reactant2-(4-chloro-1H-indol-3-yl)acetonitrileHCID 4300659—
ReactantButyllithiumHCID 178418339—
Product4-Chloro-3-cyanomethyl-indole-1-carboxylic acid methylamideHCID 23589051—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-fdb466c4e6fb46109c4b5f4548acd588
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)