HCID 140490343, compound → HCID 140490342, compound

HRID 31503Notes

Reaction equation

HRID 31503 reaction equation
[C:1]([NH:9][C:10]([C:12]1[CH:13]=[CH:14][C:15]([O:36]CC2C=CC=CC=2)=[C:16]([CH2:18][C:19]([NH:21][C:22]2[CH:27]=[CH:26][C:25]([C:28]([N:30]3[CH2:34][CH2:33][CH2:32][CH2:31]3)=[O:29])=[C:24]([CH3:35])[CH:23]=2)=[O:20])[CH:17]=1)=[NH:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[H][H].[Pd]>[C:1]([NH:9][C:10]([C:12]1[CH:13]=[CH:14][C:15]([OH:36])=[C:16]([CH2:18][C:19]([NH:21][C:22]2[CH:27]=[CH:26][C:25]([C:28]([N:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)=[O:29])=[C:24]([CH3:35])[CH:23]=2)=[O:20])[CH:17]=1)=[NH:11])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 140490343HCID 140490343, compound

Product 1

HCID 140490342HCID 140490342, compound

Reagents, catalysts & solvents 1

HCID 178506449HCID 178506449, compoundCatalyst

Procedure

Prepared analogously to Example 5h from 2-[5-(N-benzoyl-carbamimidoyl)-2-benzyloxy-phenyl]-N-[3-methyl-4-(pyrrolidin-1-yl-carbonyl)-phenyl]-acetamide and hydrogen/palladium on activated charcoal.

Sources & evidence

ORD record
ord-c52017fce6ee4e23a13d52426c5e8c40
Source dataset
uspto-grants-2008_09
Patent number
US07425641B2

Reaction notes

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