4-Benzyloxy-2(1H)-pyridone → 4-Benzyloxy-1-[2-(3-fluoro-4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one
Reaction equation
[Br:42][CH2:43][C:44]([c:45]1[cH:46][cH:47][c:48]([CH2:49][OH:50])[c:51]([F:54])[cH:52]1)=[O:53].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:26])[n:12]([CH2:15][C:16](=[O:17])[c:18]2[cH:19][cH:20][c:21]([CH2:24][OH:25])[cH:22][cH:23]2)[cH:13][cH:14]1.[CH2:27]([O:28][c:29]1[cH:30][cH:31][nH:32][c:33](=[O:34])[cH:35]1)[c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:26])[n:12]([CH2:15][C:16](=[O:17])[c:18]2[cH:19][cH:20][c:21]([CH2:24][OH:25])[c:22]([F:54])[cH:23]2)[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-662942dce4bc446daec5b25a427bda02
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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