HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 315724Generated: October 31, 2026
1,4-Dioxane → N-Cyclopropylmethyl-6-[3-(3,4-difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide
https://huagongshe.com/reaction/315724
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | 6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 66718164 | — |
| Product | N-Cyclopropylmethyl-6-[3-(3,4-difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide | HCID 46928966 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-c3d43647d1934e2cb574d2dc70894130 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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