5-Benzyloxy-2,2-dimethyl-1,3-dioxane → 2-(Phenylmethoxy)-1,3-propanediol

Participants

Reaction Steps

To a methanol (50 ml) solution of the 5-(benzyloxy)-2,2-dimethyl-1,3-dioxane (6.5 g, 29.2 mmol) obtained in the step (9b), DOWEX® 50W-X8 (5 g) was added and stirred at room temperature. After 2 hours, the reaction mixture was filtered and concentrated to obtain the title compound (5.0 g, 93.8%) as a colorless oil.

Provenance & Evidence