4-Hydroxypyrrolidine → 1-(3-Hydroxypyrrolidin-1-yl)-6-methoxy-4-phenylisoquinoline-3-carbonitrile
Reaction equation
[CH2:1]([NH:2][c:5]1[n:6][c:7]([C:23]#[N:24])[c:8](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:9]2[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][c:14]12)[CH:3]=[CH2:4].[NH:25]1[CH2:26][CH:27]([OH:30])[CH2:28][CH2:29]1>>[c:5]1([N:25]2[CH2:26][CH:27]([OH:30])[CH2:28][CH2:29]2)[n:6][c:7]([C:23]#[N:24])[c:8](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:9]2[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][c:14]12Participants
3
Sources & evidence
- ORD record
- ord-1b96a2c27dc9426a80bfd8a97fdead69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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