3-(4-bromo-2-hydroxyphenyl)-3-hydroxy-1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1,3-dihydro-2H-indol-2-one → 3-(4,5-difluoro-2-hydroxyphenyl)-1-(diphenylmethyl)-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:34][c:35]1[cH:36][cH:37][c:38]([C:39]2([OH:40])[c:41]3[c:42]([cH:43][cH:44][cH:45][cH:46]3)[N:47]([CH2:48][c:49]3[o:50][c:51]([C:52]([F:53])([F:54])[F:55])[cH:56][cH:57]3)[C:58]2=[O:59])[c:60]([OH:61])[cH:62]1.[F:1][c:2]1[cH:3][c:4]([OH:33])[c:5]([C:9]2([OH:32])[C:10](=[O:31])[N:11]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]32)[cH:6][c:7]1[F:8]>>[F:1][c:2]1[cH:3][c:4]([OH:33])[c:5]([CH:9]2[C:10](=[O:31])[N:11]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]32)[cH:6][c:7]1[F:8]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-372c6c5e71d84adcadc8b09c120ec2b1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…