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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 316596Generated: October 26, 2026

Tetrahydrofuran → 3-(3-Fluoro-4-(pyrrolidin-1-ylmethyl)phenyl)-3-hydroxycyclobutanecarboxylic acid

https://huagongshe.com/reaction/316596

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant3-Oxocyclobutane-1-carboxylic acidHCID 4913358—
Reactant1-(4-Bromo-2-fluorobenzyl)pyrrolidineHCID 22266723—
ReactantButyllithiumHCID 178418339—
Product3-(3-Fluoro-4-(pyrrolidin-1-ylmethyl)phenyl)-3-hydroxycyclobutanecarboxylic acidHCID 67278712—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-cac19ac6241b4d1589b5247b2503ed9d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)