Potassium Cation → 5-bromo-N-(1-cyclohexyl-5-(piperidin-1-ylmethyl)-1H-benzo[d]imidazol-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-3-amine
Reaction equation
[Br:24][c:25]1[cH:26][c:27]2[c:28]([I:42])[n:29][n:30]([CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:39])([CH3:40])[CH3:41])[c:31]2[cH:32][cH:33]1.[CH2:51]1[O:52][CH2:53][CH2:54][O:55][CH2:56]1.[CH:1]1([n:7]2[c:8]([NH2:23])[n:9][c:10]3[c:11]2[cH:12][cH:13][c:14]([CH2:16][N:17]2[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[K+:48].[K+:49].[K+:50].[O:59]=[C:60]([CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)[CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[O:95]=[C:96]([CH:97]=[CH:98][c:99]1[cH:100][cH:101][cH:102][cH:103][cH:104]1)[CH:105]=[CH:106][c:107]1[cH:108][cH:109][cH:110][cH:111][cH:112]1.[P:43]([O-:44])([O-:45])([O-:46])=[O:47].[Pd:57].[Pd:58]>>[CH:1]1([n:7]2[c:8]([NH:23][c:28]3[c:27]4[cH:26][c:25]([Br:24])[cH:33][cH:32][c:31]4[n:30]([CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:39])([CH3:40])[CH3:41])[n:29]3)[n:9][c:10]3[c:11]2[cH:12][cH:13][c:14]([CH2:16][N:17]2[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-816ff4f74a394bb8b373d73c60f637c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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