Acetone → tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate

HRID 316934Notes

Reaction equation

HRID 316934 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[C:1](=[O:2])([O-:3])[O-:4].[CH2:7]([C:8]#[CH:9])[Br:10].[CH3:24][C:25](=[O:26])[CH3:27].[K+:5].[K+:6]>>[CH:7]#[C:8][CH2:9][N:21]1[CH2:20][CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:23][CH2:22]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 7842Propargyl bromideHCID 19660Carbonate IonHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 11287538tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-9b9c38ae747c431e972b18bcc8849054
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…