1-Benzyl-5-methyl-1H-pyrimidine-2,4-dione → 1-benzyl-3-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}-2,2-dimethylpropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
Reaction equation
[CH2:25]([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[n:32]1[c:33](=[O:40])[nH:34][c:35](=[O:39])[c:36]([CH3:38])[cH:37]1.[Cl:1][CH2:2][C:3]([CH2:4][N:5]1[CH2:6][CH2:7][N:8]([c:11]2[c:12]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:13][cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1)([CH3:23])[CH3:24]>>[CH2:2]([C:3]([CH2:4][N:5]1[CH2:6][CH2:7][N:8]([c:11]2[c:12]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:13][cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1)([CH3:23])[CH3:24])[n:34]1[c:33](=[O:40])[n:32]([CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:37][c:36]([CH3:38])[c:35]1=[O:39]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a7806c69723c463ea30f76aaf5b408e0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…