1-(3-(Trifluoromethyl)phenyl)piperazine → 2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]-5,6-dihydro-4H-imidazo [4,5,1-ij]quinoline

HRID 317419Notes

Reaction equation

HRID 317419 reaction equation
[CH:14]([Cl:15])([Cl:16])[Cl:17].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][c:8]3[c:13]2[n:12]1[CH2:11][CH2:10][CH2:9]3.[F:18][C:19]([c:20]1[cH:21][c:22]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:23][cH:24][cH:25]1)([F:32])[F:33]>>[c:2]1([N:29]2[CH2:28][CH2:27][N:26]([c:22]3[cH:21][c:20]([C:19]([F:18])([F:32])[F:33])[cH:25][cH:24][cH:23]3)[CH2:31][CH2:30]2)[n:3][c:4]2[cH:5][cH:6][cH:7][c:8]3[c:13]2[n:12]1[CH2:11][CH2:10][CH2:9]3

Participants

4

Reactant 3

HCID 42961-(3-(Trifluoromethyl)phenyl)piperazineHCID 6212ChloroformHCID 152871052-Chloro-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline

Product 1

HCID 189819432-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]-5,6-dihydro-4H-imidazo [4,5,1-ij]quinoline

Sources & evidence

ORD record
ord-8e072dc1ce6d4b12ad4fe338eef01546
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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