2,4-Dichloro-5-(trifluoromethyl)pyrimidine → Diethyl [(5-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}-6-methoxypyridin-2-yl)methyl]phosphonate
Reaction equation
[CH2:40]([CH3:41])[O:42][P:43]([O:44][CH2:45][CH3:46])(=[O:47])[CH2:48][c:49]1[n:50][c:51]([O:56][CH3:57])[c:52]([NH2:55])[cH:53][cH:54]1.[Cl:1][c:2]1[c:3]([C:4]([F:5])([F:6])[F:7])[cH:8][n:9][c:10]([NH:11][c:12]2[cH:13][cH:14][c:15]([CH2:16][P:17](=[O:18])([O:19][CH2:20][CH3:21])[O:22][CH2:23][CH3:24])[cH:25][cH:26]2)[n:27]1.[Cl:28][c:29]1[n:30][cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[c:33]([Cl:35])[n:34]1>>[c:29]1([NH:55][c:52]2[c:51]([O:56][CH3:57])[n:50][c:49]([CH2:48][P:43]([O:42][CH2:40][CH3:41])([O:44][CH2:45][CH3:46])=[O:47])[cH:54][cH:53]2)[n:30][cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[c:33]([Cl:35])[n:34]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-340f4b888ee342d4a953a02bb1b5762e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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