2-Chloromethyl-1,4-dimethoxy-naphthalene → tert-butyl (3RS,4RS)-3-(1,4-dimethoxy-naphthalen-2-ylmethoxy)-4-[4-(4-phenyl-butoxy)-phenyl]-piperidine-1-carboxylate
Reaction equation
[Cl:32][CH2:33][c:34]1[c:35]([O:46][CH3:47])[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[c:42]([O:44][CH3:45])[cH:43]1.[OH:1][CH:2]1[CH2:3][N:4]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:12][cH:13]1)[CH2:33][c:34]1[c:35]([O:46][CH3:47])[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[c:42]([O:44][CH3:45])[cH:43]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-518456bc9cef4eb48f54b751e25b6025
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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