Methyl 3-cyclohexyl-2-[4-fluoro-2-[2-[5-(methylamino)pentylamino]-2-oxoethoxy]phenyl]-1-methylindole-6-carboxylate → Methyl 3-cyclohexyl-2-[4-fluoro-2-[2-[5-[methyl(sulfamoyl)amino]pentylamino]-2-oxoethoxy]phenyl]-1-methylindole-6-carboxylate
Reaction equation
[CH:1]1([c:7]2[c:8](-[c:21]3[c:22]([O:27][CH2:28][C:29](=[O:30])[NH:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][N:37]([S:38]([NH2:39])(=[O:40])=[O:41])[CH3:42])[cH:23][cH:24][cH:25][cH:26]3)[n:9]([CH3:20])[c:10]3[cH:11][c:12]([C:16](=[O:17])[O:18][CH3:19])[cH:13][cH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:43]1([c:44]2[c:45]3[c:46]([cH:47][c:48]([C:49]([O:50][CH3:51])=[O:52])[cH:53][cH:54]3)[n:55]([CH3:56])[c:57]2-[c:58]2[cH:59][cH:60][c:61]([F:69])[cH:62][c:63]2[O:64][CH2:65][C:66]([NH:67][CH2:68][CH2:70][CH2:71][CH2:72][CH2:73][NH:74][CH3:75])=[O:76])[CH2:77][CH2:78][CH2:79][CH2:80][CH2:81]1>>[CH:1]1([c:7]2[c:8](-[c:21]3[c:22]([O:27][CH2:28][C:29](=[O:30])[NH:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][N:37]([S:38]([NH2:39])(=[O:40])=[O:41])[CH3:42])[cH:23][c:24]([F:69])[cH:25][cH:26]3)[n:9]([CH3:20])[c:10]3[cH:11][c:12]([C:16](=[O:17])[O:18][CH3:19])[cH:13][cH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c3eb3340c704be0a563ff1a9e1126d6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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