3-(4-Methylpiperazin-1-yl)aniline → [8-(4-Methanesulfonyl-phenoxy)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

HRID 318059Notes

Reaction equation

HRID 318059 reaction equation
[CH3:22][N:23]1[CH2:24][CH2:25][N:26]([c:29]2[cH:30][c:31]([NH2:32])[cH:33][cH:34][cH:35]2)[CH2:27][CH2:28]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6]([O:10][c:11]3[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]3)[cH:7][cH:8][cH:9]2)[n:21]1>>[c:2]1([NH:32][c:31]2[cH:30][c:29]([N:26]3[CH2:25][CH2:24][N:23]([CH3:22])[CH2:28][CH2:27]3)[cH:35][cH:34][cH:33]2)[n:3][n:4]2[c:5]([c:6]([O:10][c:11]3[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]3)[cH:7][cH:8][cH:9]2)[n:21]1

Participants

3

Reactant 2

HCID 115646133-(4-Methylpiperazin-1-yl)anilineHCID 674813922-Chloro-8-(4-methanesulfonyl-phenoxy)-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 67481409[8-(4-Methanesulfonyl-phenoxy)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine

Sources & evidence

ORD record
ord-837018a4823c4709b61f44a4a519cb25
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…