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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 318079Generated: October 25, 2026

Carbonate Ion → Tert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylate

https://huagongshe.com/reaction/318079

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbonate IonHCID 19660—
ReactantPalladiumHCID 23938—
Reactant1,4-DioxaneHCID 31275—
ReactantDibenzylidene acetoneHCID 95417—
ReactantCesium cationHCID 104967—
Reactant1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
Reactant1,1-Dimethylethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylateHCID 22562205—
Reactant5-bromo-N-(3,5-difluorophenyl)nicotinamideHCID 41601149—
ProductTert-butyl 1-[5-[(3,5-difluorophenyl)carbamoyl]-3-pyridinyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxylateHCID 67265700—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-93c13f115935437b9b6afb746bf20d90
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)