化工社化工社 化学情報印刷レポート · 研究参考用
Methylamine → 6-chloro-N-methyl-3-nitropyridin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | 6-Chloro-2-dimethylamino-3-nitropyridine | HCID 21787625 | — |
| 生成物 | 6-chloro-N-methyl-3-nitropyridin-2-amine | HCID 10750094 | — |
反応手順
6-chloro-2-methylamino-3-nitro-pyridine was prepared in accordance to the procedure described above for the preparation of 6-chloro-2-dimethylamino-3-nitro pyridine by using solution of methyl amine. The crude product was purified by flash chromatography, eluting with 90% hexane: 10% ethyl acetate to 16 (300 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07425557B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-28a6a2630152406486bf79fccdaebfea |
| 出典メモ | uspto-grants-2008_09 |