6-Chloro-2-methoxy-3-nitropyridine → 6-Chloro-2-methoxynicotinonitrile

HRID 31829Notes

Reaction equation

HRID 31829 reaction equation
Cl[C:2]1[C:7]([C:8]([NH2:10])=O)=[CH:6][CH:5]=[C:4]([Cl:11])[N:3]=1.ClC1N=[C:17]([O:19]C)C([N+]([O-])=O)=CC=1>>[Cl:11][C:4]1[N:3]=[C:2]([O:19][CH3:17])[C:7]([C:8]#[N:10])=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 107977036-Chloro-2-methoxy-3-nitropyridineHCID 221427782,6-Dichloropyridine-3-carboxamide

Product 1

HCID 143811116-Chloro-2-methoxynicotinonitrile

Procedure

6-chloro-2-methoxypyridine-3-carbonitrile was prepared from 2,6-dichloro-pyridine-3-carboxamide in accordance with the procedure described above for the preparation of 6-chloro-2-methoxy-3-nitro-pyridine.

Sources & evidence

ORD record
ord-2ad86ab2f344481192c87d30651df5a4
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Reaction notes

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