Methanol → 3-{[5-(Aminomethyl)-2-chlorophenyl]oxy}-5-chlorobenzonitrile

HRID 318292Notes

Reaction equation

HRID 318292 reaction equation
[CH3:33][OH:34].[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([Cl:29])[cH:13][cH:14][c:15]([CH2:17][N:18]3[C:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][cH:25][cH:26]4)[C:27]3=[O:28])[cH:16]2)[cH:9]1.[NH2:31][NH2:32].[OH2:30]>>[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([Cl:29])[cH:13][cH:14][c:15]([CH2:17][NH2:18])[cH:16]2)[cH:9]1

Participants

5

Reactant 4

HCID 887MethanolHCID 962WaterHCID 9321HydrazineHCID 594515253-chloro-5-({2-chloro-5-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}oxy)benzonitrile

Product 1

HCID 594514053-{[5-(Aminomethyl)-2-chlorophenyl]oxy}-5-chlorobenzonitrile

Sources & evidence

ORD record
ord-c4aa571fbf2c45d9b46f775750d86d5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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