Sodium ion → 3-(3-{5-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}-1,2,4-oxadiazol-5-yl)propanoic acid

HRID 318351Notes

Reaction equation

HRID 318351 reaction equation
[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][n:13][c:14](-[c:16]4[n:17][o:18][c:19]([CH2:21][CH2:22][C:23](=[O:24])[O:25][CH2:26][CH3:27])[n:20]4)[s:15]3)[CH2:9][CH2:10]2)[cH:28][c:29]([F:32])[cH:30][cH:31]1.[Na+:34].[OH-:33]>>[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][n:13][c:14](-[c:16]4[n:17][o:18][c:19]([CH2:21][CH2:22][C:23](=[O:24])[OH:25])[n:20]4)[s:15]3)[CH2:9][CH2:10]2)[cH:28][c:29]([F:32])[cH:30][cH:31]1

Participants

4

Reactant 3

HCID 923Sodium ionHCID 961HydroxideHCID 66696811Ethyl 3-(3-{5-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}-1,2,4-oxadiazol-5-yl)propanoate

Product 1

HCID 597381823-(3-{5-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}-1,2,4-oxadiazol-5-yl)propanoic acid

Sources & evidence

ORD record
ord-ced9c56bb8cb458a9059d498ffb3ecf2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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