Methanol → 7-amino-4-(4-hydroxycyclohexyl)-2-methyl-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[BH4-:20].[CH3:22][OH:23].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:13]2[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2.[Na+:21]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:13]2[CH2:14][CH2:15][CH:16]([OH:19])[CH2:17][CH2:18]2)[c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH3:12])[CH2:7]2Participants
5
Sources & evidence
- ORD record
- ord-62fa4a168d8c4033bf0c9bf80b6720c2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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