Ethanol → (1RS,2SR)-2-amino-1-(3-furanyl)-3-(4-(trifluoromethyl)phenyl)-1-propanol

HRID 318705Notes

Reaction equation

[CH3:25][CH2:26][OH:27].[Na+:24].[OH-:23].[o:1]1[cH:2][c:3]([CH:6]2[CH:7]([CH2:12][c:13]3[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]3)[NH:8][C:9](=[O:11])[O:10]2)[cH:4][cH:5]1>>[o:1]1[cH:2][c:3]([CH:6]([CH:7]([NH2:8])[CH2:12][c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[OH:10])[cH:4][cH:5]1

Participants

Reactant 4

HCID 702Ethanol

HCID 923Sodium ion

HCID 961Hydroxide

HCID 22261716(4RS,5SR)-5-(3-furanyl)-4-((4-(trifluoromethyl)phenyl)methyl)-1,3-oxazolidin-2-one

Product 1

HCID 22262061(1RS,2SR)-2-amino-1-(3-furanyl)-3-(4-(trifluoromethyl)phenyl)-1-propanol

Sources & evidence

ORD record: ord-5b3a7a1690b54a6aaac8af05710fc63d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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