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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31873Generated: October 25, 2026

2-Chloro-5-(trifluoromethyl)pyridine → [4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]{2-[(5-trifluoromethyl(2-pyridyl))amino]ethyl}amine

https://huagongshe.com/reaction/31873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
ReactantChir-98023HCID 9847557—
Product[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]{2-[(5-trifluoromethyl(2-pyridyl))amino]ethyl}amineHCID 22142836—

Reaction Steps

[4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl](2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine (71480) was prepared from 2-chloro-5-(trifluoro-methyl)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425557B2
Source datasetuspto-grants-2008_09
ORD IDord-ea14ff6080494cf9b5a9fb52fcff269e
Source noteuspto-grants-2008_09