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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31884Generated: October 25, 2026

4-Fluoro-2-(trifluoromethyl)benzoyl chloride → {4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

https://huagongshe.com/reaction/31884

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(trifluoromethyl)benzoyl chlorideHCID 605680—
ReactantChir-98023HCID 9847557—
Product{4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amineHCID 22142951—

Reaction Steps

{4-[4-fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}{2-[(5-nitro(2-pyridyl))amino]ethyl}amine was prepared from 4-fluoro-2-(trifluoromethyl)benzoyl chloride using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425557B2
Source datasetuspto-grants-2008_09
ORD IDord-c68b266a08b440bbaf80b61c807e58ec
Source noteuspto-grants-2008_09