Potassium Cation → 1-(5-{3-[(5-Chloro-4-methoxypyrimidin-2-yl)amino]-5-methylphenyl}-1,3-thiazol-2-yl)cyclobutanol
Reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:10])[c:6]([O:8][CH3:9])[n:7]1.[K+:33].[K+:34].[NH2:11][c:12]1[cH:13][c:14](-[c:19]2[cH:20][n:21][c:22]([C:24]3([OH:28])[CH2:25][CH2:26][CH2:27]3)[s:23]2)[cH:15][c:16]([CH3:18])[cH:17]1.[O:37]=[C:38]([CH:39]=[CH:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)[CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[O:55]=[C:56]([CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)[CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[O:73]=[C:74]([CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1)[CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1.[Pd:35].[Pd:36]>>[c:2]1([NH:11][c:12]2[cH:13][c:14](-[c:19]3[cH:20][n:21][c:22]([C:24]4([OH:28])[CH2:25][CH2:26][CH2:27]4)[s:23]3)[cH:15][c:16]([CH3:18])[cH:17]2)[n:3][cH:4][c:5]([Cl:10])[c:6]([O:8][CH3:9])[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-468109cbce3e4cfeb3cc6a81a235be04
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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