Chlorotrimethylsilane → 2-Trimethylsilylthiazole

HRID 318948Notes

Reaction equation

HRID 318948 reaction equation
[Br:1][c:2]1[s:3][cH:4][cH:5][n:6]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:12][Si:13]([CH3:14])([CH3:15])[Cl:16].[CH3:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[c:2]1([Si:13]([CH3:12])([CH3:14])[CH3:15])[s:3][cH:4][cH:5][n:6]1

Participants

5

Reactant 4

HCID 6397ChlorotrimethylsilaneHCID 8058HexaneHCID 764302-BromothiazoleHCID 178418339Butyllithium

Product 1

HCID 5884532-Trimethylsilylthiazole

Sources & evidence

ORD record
ord-e99bb2c1f07f45a687d03090cf67c0e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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