2-Chloro-5-nitropyridine → HCID 178430855, compound

HRID 31907Notes

Reaction equation

HRID 31907 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:13]=1[C:19]1[C:24]([C:25]2[NH:26][CH:27]=[C:28]([CH3:30])[N:29]=2)=[CH:23][N:22]=[C:21]([NH:31][CH2:32][CH2:33][NH:34]C2N=CC(C#N)=CC=2)[N:20]=1>>[Cl:11][C:12]1[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:13]=1[C:19]1[C:24]([C:25]2[NH:26][CH:27]=[C:28]([CH3:30])[N:29]=2)=[CH:23][N:22]=[C:21]([NH:31][CH2:32][CH2:33][NH:34][C:2]2[CH:3]=[CH:4][C:5]([N+:8]([O-:10])=[O:9])=[CH:6][N:7]=2)[N:20]=1

Participants

3

Reactant 2

HCID 783082-Chloro-5-nitropyridineHCID 178430853HCID 178430853, compound

Product 1

HCID 178430855HCID 178430855, compound

Procedure

[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine was prepared from 6-chloro-3-nitropyridine using the general method for 6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile.

Sources & evidence

ORD record
ord-ab30e9dc5f12411082ee43cd69c01ed2
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Reaction notes

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