Dichloromethane → Tert-butyl 4-fluorocyclohexanecarboxylate

HRID 319169Notes

Reaction equation

HRID 319169 reaction equation
[CH2:15]([N:16]([S:17]([F:18])([F:19])[F:21])[CH2:20][CH3:22])[CH3:23].[Cl:24][CH2:25][Cl:26].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[CH:2]1([F:21])[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 123472(Diethylamino)sulfur trifluorideHCID 16064595trans-tert-Butyl 4-hydroxycyclohexanecarboxylate

Product 1

HCID 57672260Tert-butyl 4-fluorocyclohexanecarboxylate

Sources & evidence

ORD record
ord-0ae4fcde76ce44dbbc1bd31cb2fa1647
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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