Methanol → 8-Fluoro-2-isopropyl-4-methyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-ol
Reaction equation
[CH3:34][OH:35].[F:1][c:2]1[cH:3][cH:4][c:5]([OH:28])[c:6]2[c:7]([CH3:27])[c:8]([CH2:15][c:16]3[cH:17][cH:18][c:19](-[n:22]4[n:23][cH:24][cH:25][cH:26]4)[cH:20][cH:21]3)[c:9]([C:12](=[CH2:13])[CH3:14])[n:10][c:11]12.[H:29][H:30].[OH-:31].[OH-:33].[Pd+2:32]>>[F:1][c:2]1[cH:3][cH:4][c:5]([OH:28])[c:6]2[c:7]([CH3:27])[c:8]([CH2:15][c:16]3[cH:17][cH:18][c:19](-[n:22]4[n:23][cH:24][cH:25][cH:26]4)[cH:20][cH:21]3)[c:9]([CH:12]([CH3:13])[CH3:14])[n:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7d26b3b5ac8e45088c886705428a0ba3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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