HCID 178430875, compound → HCID 178430856, compound

HRID 31929Notes

Reaction equation

HRID 31929 reaction equation
Cl.Cl.[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C:11]1[C:16]([C:17]2C=CN[N:18]=2)=[CH:15][N:14]=[C:13]([NH:22][CH2:23][CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][N:27]=2)[N:12]=1.[Cl:35]C1C=C(Cl)C=CC=1[C:43](=O)[C:44](C1NC=C(C)N=1)=[CH:45][N:46](C)C>>[ClH:3].[ClH:35].[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C:11]1[C:16]([C:17]2[NH:46][CH:45]=[C:44]([CH3:43])[N:18]=2)=[CH:15][N:14]=[C:13]([NH:22][CH2:23][CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][N:27]=2)[N:12]=1

Participants

3

Reactant 2

HCID 178430875HCID 178430875, compoundHCID 178478900HCID 178478900, compound

Product 1

HCID 178430856HCID 178430856, compound

Procedure

Made using the same procedure as for [4-(2,4-dichlorophenyl)-5-pyrazolylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine dihydrochloride except that 1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-(4-methylimidazolyl)prop-2-en-1-one (XI, 421 mg, 1.3 mmol) was used.

Sources & evidence

ORD record
ord-95a99574fb9740e696c86b89859ac1d2
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Reaction notes

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