HCID 178432791, compound → HCID 178432628, compound

HRID 31931Notes

Reaction equation

HRID 31931 reaction equation
Cl.Cl.[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C:11]1[C:16]([C:17]2C=CN[N:18]=2)=[CH:15][N:14]=[C:13]([NH:22][CH2:23][CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][N:27]=2)[N:12]=1.[Cl:35]C1C=C(Cl)C=CC=1C(=O)[C:44](C1N=C(C)NC=1)=[CH:45][N:46](C)[CH3:47]>>[ClH:3].[ClH:35].[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:5]=1[C:11]1[C:16]([C:17]2[N:18]=[C:45]([CH3:44])[NH:46][CH:47]=2)=[CH:15][N:14]=[C:13]([NH:22][CH2:23][CH2:24][NH:25][C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[CH:28][N:27]=2)[N:12]=1

Participants

3

Reactant 2

HCID 178432791HCID 178432791, compoundHCID 178478900HCID 178478900, compound

Product 1

HCID 178432628HCID 178432628, compound

Procedure

Made using the same procedure as for [4-(2,4-dichlorophenyl)-5-pyrazolylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine dihydrochloride except that 1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-(2-methylimidazolyl)prop-2-en-1-one (XV, 421 mg, 1.3 mmol) was used.

Sources & evidence

ORD record
ord-d2d082c004854e43a765da725c4a645f
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Reaction notes

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